Donington and Stiles Describe the Surgical Implications of Lung Cancer Treatment Evolutions

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Drs Donington and Stiles discuss how the findings from the ADAURA trial with adjuvant osimertinib have changed thoracic surgery expectations, the potential surgical implications of the ALINA trial with adjuvant alectinib, and the importance of early-stage molecular testing in lung cancer.

Welcome to OncLive On Air®! I’m your host today, Caroline Seymour.

OncLive On Air is a podcast from OncLive®, which provides oncology professionals with the resources and information they need to provide the best patient care. In both digital and print formats, OncLive covers every angle of oncology practice, from new technology to treatment advances to important regulatory decisions.

In today’s episode, sponsored by AstraZeneca, we had the pleasure of speaking with Jessica S. Donington, MD, MSCR, and Brendon M. Stiles, MD, about surgical perspectives on key lung cancer treatment developments. Dr Donington is a professor of surgery and chief of the Section of Thoracic Surgery in the Department of Surgery at the University of Chicago in Illinois. Dr Stiles is chief of Thoracic Surgery and Surgical Oncology, as well as the associate director of Surgical Oncology at Montefiore Einstein Comprehensive Cancer Center in the Bronx, New York, where he is also a professor in the Department of Cardiothoracic & Vascular Surgery, a professor in the Department of Oncology (Medical Oncology), and a professor in the Department of Medicine (Oncology & Hematology).

In part 1 of our exclusive 2-part interview, Drs Donington and Stiles discussed how the findings from the phase 3 ADAURA trial (NCT02511106) with adjuvant osimertinib (Tagrisso) have changed thoracic surgery expectations, the potential surgical implications of the phase 3 ALINA trial (NCT03456076) with adjuvant alectinib (Alecensa), and the importance of early-stage molecular testing in lung cancer.

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