Dr. Lencioni on Assessing Response to HCC Therapy

Riccardo Lencioni, MD, professor in the Department of Radiology at the University of Pisa School of Medicine in Pisa, Italy, discusses how response to hepatocellular carcinoma (HCC) treatment can be best assessed in patients.

For patients who receive locoregional therapies, there is a general consensus that using modified Response Evaluation Criteria in Solid Tumors (mRECIST) provides useful and reliable predictors of patient survival. However, there are emerging data that mRECIST criteria may also be an independent predictor of survival for patients with advanced HCC who are receiving systemic therapies.

Applying these criteria in assessing patient response to treatment will be increasingly important as the treatment landscape for HCC expands with the addition of new agents. Understanding which patients benefit most from particular therapies will be of particular value in tailoring patient care.

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