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Impact of Off-Target AEs and Treatment Resistance on Evolving 1L Therapy Strategies for CLL
January 12th 2024Javier Pinilla, MD, PhD, provides a brief overview of the changing CLL treatment landscape, discussing the influence of off-target adverse events and the development of treatment resistance on the evolution of BTK inhibitor therapy.
Exploring BTKi Monotherapy in CLL: Long-Term Updates from ELEVATE-TN and SEQUOIA
January 12th 2024Brian Hill, MD, PhD, discusses the use of BTK inhibitor monotherapy in CLL and presented recent long-term data updates from studies such as the 6-year follow-up of ELEVATE-TN and the extended follow-up from SEQUOIA.
Khouri Highlights the Ongoing AFFIRM-AL Trial in AL Amyloidosis
November 9th 2023Dr Khouri discusses unmet needs in AL amyloidosis, the potential for birtamimab to become a new frontline standard of care, and the importance of confirming earlier post-hoc results from the VITAL trial in the AFFIRM-AL trial in patients with Mayo stage IV AL amyloidosis with cardiac involvement.
Holistic and Multidisciplinary Approaches to Multiple Myeloma Management
Closing out their program on multiple myeloma, expert panelists consider the role of holistic and multidisciplinary care when managing patients within the current paradigm.
Impact of Clinical Trials on the Management of Multiple Myeloma
Continuing its discussion on clinical trials in multiple myeloma, the panel emphasizes the impact that data may have on the real-world treatment landscape.
Importance of Clinical Trial Enrollment in Multiple Myeloma
Key opinion leaders in multiple myeloma management elucidate the value of clinical trials and share enthusiasm for improving enrollment when possible.
Multiple Myeloma: Regulatory Aspects of Treatment Development and Approval
A focused discussion on the regulatory aspects of drug testing and approval, globally, with respect to the setting of multiple myeloma management.
Educating Patients on Treatment Options for Multiple Myeloma
Expert panelists consider best methods in educating patients on their options for therapy following a diagnosis of multiple myeloma.
Treatment for Newly Diagnosed Multiple Myeloma: Addressing Disparities in Care
Comprehensive insight to disparities that may impact a patient’s access to therapy for multiple myeloma and how these may be overcome.
Treatment Considerations for Patients with Newly Diagnosed Multiple Myeloma
Panelists share a brief discussion on the current treatment armamentarium available to patients with newly diagnosed multiple myeloma.
Role of Diagnostic Testing in Patients with Multiple Myeloma
Experts in multiple myeloma management consider essential tests that aid in the diagnosis and treatment of newly presenting patients.
Biomarker Analysis Contextualizes RFS Benefit With Nivolumab in Metastatic Melanoma
September 1st 2023Brian Gastman MD, discusses how findings from CheckMate76K contributed to the rationale for a biomarker analysis in that trial’s patient population, key findings from this biomarker analysis, and how these findings may inform further research regarding the benefits of immunotherapy in earlier-stage disease.
Momelotinib Could Represent Pivotal New Treatment Option in Myelofibrosis
Aaron T. Gerds, MD, PhD, expands on the potential role of momelotinib in the treatment of patients with myelofibrosis who present with anemia, details the data from MOMENTUM, and explains what FDA approval of momelotinib could mean for the treatment of this patient population.
Rural Patient Populations at Higher Risk of Lung Cancer Mortality
Logan Roof, MD, discusses the importance of investigating demographic disparities that exist in lung cancer mortality, expands on the results of the population-based CDC database analysis, and discusses potential next steps to address these disparities in the future.
Enfortumab Vedotin Plus Pembrolizumab Sustains Long-Term Benefit in Metastatic Urothelial Carcinoma
Shilpa Gupta, MD, expands on the updated results from EV-103 in patients with locally advanced or metastatic urothelial carcinoma who are ineligible for cisplatin, and details the next steps for investigating the combination of enfortumab vedotin plus pembrolizumab in the ongoing phase 3 EV-302 trial.