Expert Perspectives on Differentiating Signs and Symptoms in AL Amyloidosis Diagnosis
Vaishali Sanchorawala, MD, examines the signs and symptoms linked to AL amyloidosis, underscoring that distinctive symptoms may not manifest in patients until later stages of the disease, potentially causing delays in diagnosis.
EP: 1.Exploring the Landscape Surrounding Light Chain Amyloidosis
EP: 2.Expert Perspectives on Differentiating Signs and Symptoms in AL Amyloidosis Diagnosis
EP: 3.Exploring Diagnostic Approaches for Patients with Light Chain Amyloidosis
EP: 4.Current Treatment Landscape for AL Amyloidosis
EP: 5.Unmet Needs and Treatment Considerations in Managing AL Amyloidosis
EP: 6.Treatment Strategies Using Monoclonal Antibodies in AL Amyloidosis
EP: 7.Optimizing Treatment Management Strategies in AL Amyloidosis with CD38-Directed mAbs
EP: 8.Addressing Challenges in Managing AL Amyloidosis with Cardiac Involvement
EP: 9.The Role of Cardiac Staging in Patients with AL Amyloidosis
EP: 10.Novel Treatment Approaches with mAbs Targeting Amyloid Deposits: Insights from VITAL
EP: 11.AFFIRM-AL: Birtamimab in Patients with Mayo Stage IV AL Amyloidosis
EP: 12.Expert Insights on Pooled Safety Data from the PRONTO and VITAL trials
EP: 13.The Potential Role of CAR T Therapy in AL Amyloidosis
EP: 14.NEXICART-1: Safety and Efficacy of NXC-201 in AL Amyloidosis
EP: 15.Looking Ahead: Future Perspectives on AL Amyloidosis
This is a video synopsis/summary of a Peer Exchange involving Heather Landau, MD; Vaishali Sanchorawala, MD; and Jeffrey Zonder, MD.
Panelists discuss diagnostic challenges in light chain (AL) amyloidosis and underscore the rarity of the disease, necessitating a high clinical suspicion for red flag symptoms like fatigue and peripheral edema. Specific signs, including periorbital ecchymosis and tongue enlargement, are highlighted. They emphasize the rarity-related misdiagnoses, where common conditions are often considered first, delaying amyloidosis identification. They express concern for patients with nonspecific symptoms being overlooked, emphasizing the rarity challenge in diagnosis. The discussion stresses the need for heightened awareness among health care professionals to promptly detect AL amyloidosis and prevent misdiagnoses, crucial for effective management of this uncommon disease.
Video synopsis is AI-generated and reviewed by OncLive® editorial staff.
