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Sonja Althammer on Role of CD8 and PD-L1 Biomarkers for Immunotherapy in NSCLC
Susan Lutgendorf on Impact of Minimal Support on Patients With Ovarian Cancer
Lisa Butterfield on SITC Immune Biomarkers Task Force
Oncology Conference Articles
Emerging Immune Checkpoint Holds Promise for Blockade Strategies
A novel immune checkpoint called PVRIG is currently in development.
Dual Biomarker Signature Holds Predictive Promise for Response to Anti-PD-L1 Therapy in NSCLC
Recent research suggests that the presence of PD-L1–positive and CD8+ cells may be useful for predicting responses in patients with non-small cell lung cancer who have been treated with durvalumab.
Nivolumab/Ipilimumab Combo Highly Effective for Pretreated Metastatic Urothelial Carcinoma
The combination of nivolumab and ipilimumab led to a high response rate and improved overall survival versus historical controls for patients with pretreated metastatic urothelial carcinoma.
Pembrolizumab OS Benefit Sets New Benchmark in Second-Line Bladder Cancer
Pembrolizumab monotherapy reduced the risk of death by 27% compared with chemotherapy for patients with advanced urothelial carcinoma whose disease progressed after prior treatment.
Lirilumab/Nivolumab Combo Highly Effective in Head and Neck Cancer
The combination of lirilumab and nivolumab resulted in an objective response rate of 24.1% in patients with squamous cell carcinoma of the head and neck.
CAR T-Cell Therapy in DLBCL: Centers of Excellence
Study Identifies Factors Linked to Long-Term Survival in Pediatric/Adolescent DIPG
Harvard Expert Sees Potential in BCL-2 Combos
Tocilizumab Resolves CRS in Pediatric B-ALL Without Reducing Tisagenlecleucel Efficacy
Bounty of Novel Drugs Ushers In New Era for ALK-Positive NSCLC
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