Breast Cancer | Specialty

An Autopsy of Breast Cancer Management Amidst the COVID-19 Pandemic

March 7th 2021

One year into the COVID-19 pandemic has allowed for some reflection on the different evolutions that the oncology community went through in response to the many challenges posed by the virus.

Biomarkers Help Predict the Role of Chemotherapy in Biologic Aging

March 7th 2021

Stimuli for biologic aging include ionizing radiation, ultraviolet light, diet, exercise, oxidative stresses, and perhaps, worst of all, smoking. All of these can trigger intracellular processes, including DNA methylation, or epigenetic change, telomere shortening and damage, DNA damage, and mitochondrial dysfunction.

Genomics, AI, and Demography Will Remake Cancer Care by 2030

March 7th 2021

A wave of approvals and a rapidly evolving treatment landscape could make the next decade a watershed period in breast cancer care.

Addressing Treatment Disparities Among Younger Women with Breast Cancer

March 6th 2021

Even in 2021, disparities in outcomes of younger women with breast cancer vs their older counterparts remain; addressing behavioral issues and psychological concerns in this population could vastly improve their quality of life, treatment adherence, and ultimately, survival.

The Marshall Family Faces Off Against TNBC

March 6th 2021

Off Our Chests: A Candid Tour Through the World of Cancer is a memoir that dives into Liza Marshall’s breast cancer journey.

Neoadjuvant Checkpoint Inhibition Shows Promise in TNBC, But Is Not Ready for Clinical Use

March 6th 2021

Although phase 3 data suggest that the addition of checkpoint inhibitors to neoadjuvant chemotherapy could improve pathologic complete response rates for patients with early-stage triple-negative breast cancer, immature data and the risk of long-term toxicity indicate that the therapy is not ready for primetime

Dr. Kalinsky on the Potential of ADCs Across Breast Cancer Subtypes

March 6th 2021

Kevin Kalinsky, MD, MS, discusses the potential of antibody-drug conjugates across breast cancer subtypes.

Dr. Rugo on the Benefit of Margetuximab Plus Chemotherapy in HER2+ Metastatic Breast Cancer

March 6th 2021

Hope S. Rugo, MD, discusses the benefit of margetuximab-cmkb in patients with HER2-positive breast cancer who have received prior HER2-targeted therapies.

New HER2-Targeting Therapies Jostle for a Place in the Treatment Lineup

March 6th 2021

The introduction of new therapies for patients with recurrent HER2-positive metastatic breast cancer has resulted in a crowded landscape for third-line treatments and beyond, raising questions about how best to sequence a wealth of options.

Research Moves Full Steam Ahead With Brain Metastases, Leptomeningeal Disease in Breast Cancer

March 6th 2021

Targeted agents and chemotherapy regimens are at the crux of systemic research efforts focused on improving outcomes for patients with breast cancer who have brain metastases and/or leptomeningeal disease.

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