Colorectal Cancer

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The OncLive Colorectal Cancer condition center page is a comprehensive resource for clinical news and expert insights on colorectal cancer treatment and management, with a focus on novel therapeutic strategies including checkpoint inhibitors and TKIs across lines of therapy. This page features news articles, interviews in written and video format, and podcasts that focus on unmet needs, treatment advances, and ongoing research in colorectal cancer.

Latest News

Stage III Colon Cancer | Image Credit: ©   Ashling Wahner & MJH Life Sciences Using AI
Zanzalintinib Plus Atezolizumab Boosts OS in Previously Treated, Non–MSI-H mCRC

June 23rd 2025

Zanzalintinib plus atezolizumab improved overall survival in previously treated, non–MSI-H metastatic colorectal cancer.

Jessica Paulus, ScD
Real-World Analysis Suggests Social Determinants of Health May Be Associated With Early Onset of CRC

June 18th 2025

Five Under 5: Top Oncology Videos for the Week of 6/1
Five Under 5: Top Oncology Videos for the Week of 6/1

June 8th 2025

The OncFive
The OncFive: Top Oncology Updates for the Week of 6/1

June 7th 2025

Colorectal Cancer | Image credit:   © Anatomy Insider - stock.adobe.com
NCCN Adds 2 Tests to CRC Screening Guidelines

June 3rd 2025

Video Series
Video Interviews
Podcasts
Marwan G. Fakih, MD
Oncology Unplugged
Heinz-Josef Lenz, MD, FACP, about the prognostic and predictive value of HER2 gene expression for patients with KRAS wild-type metastatic colorectal cancer (mCRC). Lenz is a professor in the Department of Medicine and the Department of Preventive Medicine in the Division of Oncology at the University of Southern California (USC) Keck School of Medicine in Los Angeles. He also serves as the associate director of Clinical Research, chair of the Gastrointestinal Oncology Program, and co-director of the Colorectal Center at the USC Norris Comprehensive Cancer Center
John H. Strickler, MD
Latest CME Events & Activities

26th Annual International Lung Cancer Congress®

July 25-26, 2025

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Medical Crossfire®: Expert Perspectives on Targeting c-Met Overexpression and 𝘔𝘌𝘛 Genomic Alterations in NSCLC – Unveiling the Complexities of 𝘔𝘌𝘛 Dysregulation

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Tumor Board: Expert Insights on Managing Classical 𝘌𝘎𝘍𝘙 Mutations, 𝘌𝘎𝘍𝘙 Exon 20 Insertions, and Atypical 𝘌𝘎𝘍𝘙 Mutations in Metastatic NSCLC

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Medical Crossfire®: Harnessing the Power of Modern Therapies in Newly Diagnosed Multiple Myeloma

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Cases and Conversations™: Sorting Through the Expanding Treatment Options for Patients with Relapsed/Refractory Multiple Myeloma

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Evolving Treatment Strategies in Pancreatic Cancer: Current Standards, Emerging Targets, and the Role of Molecular Testing

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PER Tumor Board®: Applying Recent Advances to Transform the Treatment Paradigm in SCLC—Expert Perspectives on New Approvals and Emerging Strategies

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Medical Crossfire®: Integrating Next-Generation Endocrine Targeting Therapies to Improve Outcomes for Patients With HR+/HER2- Breast Cancer

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GI Tumor Board—Applying Recent Advances in Biomarker Testing and Treatment in Metastatic Colorectal Cancer

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Medical Crossfire®: Improving Patient Outcomes in Myeloproliferative Neoplasms With Novel Therapeutic Approaches

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Fighting Disparities and Saving Lives: An Exploration of Challenges and Solutions in Cancer Care

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Community Practice Connections™: 14th Asia-Pacific Primary Liver Cancer Expert Meeting

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(CME) Optimizing Management of Ocular Toxicity in Cancer Patients: The Role of Ophthalmologists in the Spectrum of Care

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(COPE) Optimizing Management of Ocular Toxicity in Cancer Patients: The Role of Ophthalmologists in the Spectrum of Care

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20th Annual New York Lung Cancers Symposium®

November 15, 2025

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PER® Liver Cancer Tumor Board: How Do Evolving Data for Immune-Based Strategies in Resectable and Unresectable HCC Impact Multidisciplinary Patient Management Today… and Tomorrow?

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Community Practice Connections™: 6th Annual Precision Medicine Symposium – An Illustrated Tumor Board

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Navigating Low-Grade Serous Ovarian Cancer – Enhancing Diagnosis, Sequencing Therapy, and Contextualizing Novel Advances

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Cases & Conversations™: Integrating Novel Approaches to Treatment in First-line ALK+ mNSCLC – Enhancing Patient Outcomes with Real World Multidisciplinary Strategies

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Burst CME™: Implementing Appropriate Recognition and Diagnosis of Low-Grade Serous Ovarian Cancer

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Burst CME™: Understanding Novel Advances in LGSOC—A Focus on New Mechanisms of Action and Clinical Trials

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Burst CME™: Stratifying Therapy Sequencing for LGSOC and Evaluating the Unmet Needs of the Standard of Care

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Community Practice Connections™: Case Discussions in TNBC… Navigating the Latest Advances and Impact of Disparities in Care

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Epithelioid Sarcoma: Applying Clinical Updates to Real Patient Cases

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Collaborating Across the Continuum®: Identifying and Treating Epithelioid Sarcoma

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Mastering Epithelioid Sarcoma: Enhancing Diagnostic Precision and Tailoring Treatment Strategies

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Clinical Showcase™: Selecting the Best Next Steps for a Patient with Epithelioid Sarcoma

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2nd Annual Hawaii Cancer Conference

January 24-25, 2026

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A Breath of Strength: Managing Cancer Associated LEMS and Lung Cancer as One

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Show Me the Data™: Bridging Clinical Gaps Along the Continuum From Resectable, Early Stage to Advanced Gastric/Gastroesophageal Junction Cancers

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