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Early lung-specific response to atezolizumab plus bevacizumab was associated with longer overall survival in patients with hepatocellular carcinoma with pulmonary metastases.

Lung Responses to Atezolizumab/Bevacizumab Linked With OS in HCC and Pulmonary Metastasis 

Second-line treatment with regorafenib displayed safety in patients with advanced hepatocellular carcinoma who were not eligible for treatment on the phase 3 RESORCE trial, according to data from the phase 2 REGAIN trial.

Second-Line Regorafenib Demonstrates Safety in Advanced HCC, Irrespective of Prior Treatment

The addition of toripalimab to standard-of-care sorafenib in the frontline setting demonstrated preliminary efficacy and tolerability in patients with unresectable hepatocellular carcinoma.

First-line Toripalimab Plus Sorafenib Elicits Responses in Unresectable Hepatocellular Carcinoma 

Uwe Platzbecker, MD, discusses the FDA approval of luspatercept for the treatment of anemia in patients who have not had prior treatment with erythropoiesis-stimulating agent and may require regular red blood cell transfusions could change the sequencing of agents for this patient population.

Data for Luspatercept Highlight Evolving Treatment Landscape in Lower-Risk MDS 

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Caroline Seymour is your initial point of contact for the 

™. She joined the company in 2018 as an assistant editor, with expertise in video production and print/digital publication. Email: 

Articles

The FDA has granted orphan drug designation to the next generation BCMA-directed CAR T-cell therapy NXC-201 for the treatment of patients with amyloid light chain amyloidosis.

FDA Grants Orphan Drug Designation to NXC-201 for AL Amyloidosis

Treatment with SLS009 generated clinical activity and was safe in patients with relapsed/refractory lymphomas.

SLS009 Demonstrates Activity, Safety in Relapsed/Refractory Lymphoma

Uwe Platzbecker, MD, discusses the efficacy and safety data from the COMMANDS trial that supported the approval, and the next steps planned for luspatercept’s investigation in patients with lower-risk MDS who are transfusion independent. 

Luspatercept Provides Frontline Alternative to ESAs For Lower-Risk MDS and Anemia

Courtney D. DiNardo, MD, MSCE, discusses ongoing investigations of triplet regimens with an azacitidine/venetoclax backbone for the treatment of patients acute myeloid leukemia and highlights the unmet needs that remain in older and high-risk subgroups within this patient population. 

Triplets With Azacitidine/Venetoclax Aim to Improve Responses in AML

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REGISTER TODAY to explore data on a novel second-generation BTK inhibitor for adult patients with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL).

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Expert provides an overview of esophageal squamous cell carcinoma (ESCC), discusses several key updates to the treatment landscape, and elucidates how clinicians can improve patient outcomes by applying data from the treatment algorithm.

My Treatment Approach: The Evolving Treatment Landscape of Esophageal Squamous Cell Carcinoma

Videos

Broad discussion from expert John Marshall, MD, on the current standards of diagnosis care in esophageal squamous cell carcinoma (ESCC).

A Survey of Patient Presentation, Testing, and Diagnosis in ESCC

Shared insights on contemporary approaches to treating localized ESCC and existing racial disparities in treatment.

Trends and Disparities in Treatment Approaches for Patients With Locoregional ESCC

Focusing on metastatic ESCC, John Marshall, MD, discusses selecting appropriate first-line treatment strategies for patients.

First-line Treatment Approaches and Considerations for Patients With Metastatic ESCC

Thoughtful discussion of existing and emerging second-line treatment options for patients with metastatic ESCC

Insights on Existing and Prospective Second-line Treatment Strategies for Patients With ESCC

My Treatment Approach: The Evolving Treatment Landscape of Esophageal Squamous Cell Carcinoma

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