February 2012

Continuous treatment with lenalidomide given early prolonged the time to progression, compared with no treatment in patients with high-risk, asymptomatic, smoldering, multiple myeloma.

The Massachusetts General Hospital (MGH) Cancer Center comprises 23 fully integrated, multidisciplinary clinical programs, as well as an extensive array of support and educational services.

It may be possible to forgo radiation in previously untreated patients with limited-stage Hodgkin lymphoma.

Vorinostat added to bortezomib improved progression-free survival compared with bortezomib plus placebo in patients with relapsed/refractory multiple myeloma.

Patients with oropharyngeal squamous cell carcinoma who had matted lymph nodes -- nodes that are connected together -- are more likely to metastasize than those without matted lymph nodes.

Treatment with tivantinib produced a 56% improvement in time-to-progression in patients with hepatocellular carcinoma.

Contrary to earlier findings, surgical breast biopsies may not be as overused as previously thought, according to a recent study published in the Journal of the American College of Radiology.

The Trials in Progress section supplies summaries of ongoing research in a broad range of cancer types.

Acupuncture may help prevent xerostomia in patients with nasopharyngeal carcinoma undergoing radiotherapy and may also reduce symptom severity.

Treatment of selected cases of localized lymphoma during the second and third trimester was associated with minimal maternal and fetal risk of complications.

Clarient provides more than 350 diagnostic tests to assess and characterize tumors, including tests for BRAF, KRAS, and EGFR gene mutations.

The burden of late complications after hematopoietic cell transplantation is high, and these late effects are associated with poor health and decreased functional status.

Combination therapy with everolimus and the octreotide LAR increases the median PFS in patients with advanced neuroendocrine tumors associated with carcinoid syndrome.

A meta-analysis shows no apparent association between androgen deprivation therapy and cardiovascular events and death in men with prostate cancer.

A closer look at 2 investigational agents, carlfilzomib and pomalidomide, that were featured at the 53rd American Society of Hematology annual meeting.

New findings suggest that increased serum glucose levels may be a risk factor for colorectal cancer in postmenopausal women.

Annual prostate cancer screening does not decrease mortality from prostate cancer more than opportunistic screening.

The Miami Breast Cancer Conference has become a well-respected and well-attended gathering that specialists make a point of returning to year after year.

In 2011, the FDA reported 232 cancer therapies to be in limited supply. As a result, many patients have had therapies delayed or discontinued, and in some cases, patients have been left without access to appropriate alternatives.