Clinical Trials in Progress
Trials underway in gastrointestinal, oral, head and neck, and brain cancer intended to stimulate discussion about ongoing clinical trials and to promote collaboration across the oncology community.
Naproxen Cuts Pegfilgrastim-Induced Bone Pain
The nonsteroidal anti-inflammatory drug naproxen significantly decreases the incidence, severity, and duration of pegfilgrastim-induced bone pain in patients diagnosed with a nonmyeloid cancer.
Long-Term Hormonal Therapy May Pose Breast Cancer Risk
The long-standing debate about postmenopausal
hormones and breast cancer gained more evidence
to support an increased cancer risk.
Modified IP Regimen for Ovarian Cancer Leads to 90% Completion Rate
A modified intraperitoneal (IP) regimen for advanced ovarian cancer demonstrated feasibility, tolerability, and evidence of effectiveness, results of a small pilot study suggest.
Payer Management of Oncology Gets Serious
Health plans continue to seek methods to curtail cancer costs.
Current Issues in Gynecologic Oncology: A Discussion With John Curtin, MD
Many contemporary issues in the US healthcare system affect clinicians in all areas of medicine. Some issues are even more specific to the field of gynecologic oncology.
Ingenol Mebutate Gel Is Effective and Safe for Actinic Keratosis
Field-directed treatment with the investigational topical agent ingenol mebutate has been shown to be effective for actinic keratoses on the head and body.
Close Call for Cost-Effectiveness of Bevacizumab in Ovarian Cancer
Recent clinical and economic studies have suggested that ovarian cancer regimens containing bevacizumab could fall within the boundaries of cost-effectiveness, at least for some patients.
Antibody Gets High Marks in Small Hepatocellular Carcinoma Trial
Three-fourths of patients with advanced hepatocellular carcinoma associated with hepatitis C infection achieved disease control with antibody therapy directed at a T-cell antigen.
University of Chicago Comprehensive Cancer Center: Innovation in Research
For nearly 40 years, the University of Chicago Comprehensive Cancer Center has enjoyed a reputation for excellence and innovation.
Vitamin D Might Benefit Patients With Prostate Cancer
The cancer proliferation marker Ki-67 decreased significantly in men who took high-dose vitamin D in the weeks leading up to radical prostatectomy for localized prostate cancer.
Maintaining a Stable Weight May Help Breast Cancer Survivors Avoid Hot Flashes
Women who have been previously treated for early-stage breast cancer are much less likely to complain of hot flashes if they remain within 10% of their prediagnosis weight.
Nab-Paclitaxel Shows Promise in Advanced Lung Cancer
The administration of nab-paclitaxel plus carboplatin results in a significantly higher ORR than conventional solvent-based paclitaxel with carboplatin in previously untreated patients with advanced NSCLC.
Breast Cancer Survival Rises With Cruciferous Vegetable Intake
Breast cancer survival improved significantly in patients who increased consumption of cruciferous vegetables following diagnosis, a study of Chinese women showed.
Diabetes Drug Emerges as Potential Therapy in Multiple Cancers
Four studies reflected the growing interest in-and the volume of evidence for-using the diabetes drug metformin as a potential cancer therapy.
Cancer May Cause Prolonged Stress Disorder
More than a third of cancer survivors report ongoing symptoms of posttraumatic stress disorder several years after being diagnosed with cancer.
Unexpected Mutations Doom Therapy for Glioblastoma
Unexpected target mutations likely doomed a proven therapeutic approach to lung cancer in a test against glioblastoma.
Older Lung Cancer Patients Do Not Benefit From Bevacizumab Added to Standard Treatment
The addition of bevacizumab to first-line carboplatin-paclitaxel did not prolong survival in Medicare recipients with advanced nonâ€“small cell lung cancer.
Breast Cancer Risk May Be Linked to Injectable Contraceptive Use
Young women who have recently used DMPA for at least 1 year have more than twice the risk of invasive breast cancer as young women who do not report recent use of the injectable contraceptive.
Epigenetics Breathes New Life Into Older Cancer Drugs
Cancer drugs once deemed too toxic for humans have earned a second chance at therapeutic utility, in part because of a reversal in the usual progression of medical research.
Another Bite of the Immunotherapy Apple
In the past few years the pace of discovery of effective immunotherapies has accelerated as a consequence of better chemistry and understanding of immune biology.
Later-Line Ruxolitinib Use Produces Ongoing Benefit in Real-World Patients With cGVHD
Orca-T Data With Survival, Tolerability Extends to Older Patients With Hematologic Cancers
Dr Ramdial on Gemcitabine/Clofarabine/Busulfan for Lymphoma Stem Cell Transplant
Retrospective Analysis Shows Post-HCT Survival Benefits With Orca-T Vs PTCy in Hematologic Malignancies
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