News|Videos|November 11, 2026

Arcotatug tavatecan (IBI343/TAK-921) versus treatment of physician’s choice (TPC) in previously treated, advanced gastric or gastroesophageal junction adenocarcinoma (G/GEJA): First interim analysis of the randomized, open-label, phase 3, G-HOPE-001 study

Rapid readout: Phase 3 GHOPE-001 shows claudin 18.2 ADC AT extends PFS/OS vs chemo in late-line gastric/GEJ cancer, manageable safety.

A clinical study compared arcotatug tavatecan against standard treatment options for patients with previously treated advanced gastric or gastroesophageal junction adenocarcinoma. The trial's findings revealed that the investigational antibody-drug conjugate significantly improved both progression-free survival and overall survival compared to the control group. Furthermore, patients treated with arcotatug tavatecan experienced durable responses with a manageable safety profile.


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