Dr. Symmans on Moon Shots Program for Patients With TNBC

William F. Symmans, MB, ChB, Division of Pathology/Lab Medicine, Department of Pathology, The University of Texas MD Anderson Cancer Center, discusses the institution's Moon Shots program for patients with triple-negative breast cancer (TNBC).

Within the program, researchers obtain biopsies of patients prior to their treatment, and are randomized to receive the results of a genomic test designed to predict response to chemotherapy. The results will impact whether patients receive the second half of weekly paclitaxel or an experimental therapy.

The objective of the program is to be able to conduct clinical trials of new treatments in the patient setting, where it is least likely a complete response will be reported, Symmans explains.

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