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Opinion|Videos|June 24, 2026

Phase 2 data from ROSETTA Lung-02, a global randomized phase 2/3 trial of pumitamig (PD-L1 × VEGF-A bsAb) + chemotherapy in 1L NSCLC

Author(s)Solange Peters, MD, PhD

This presentation presents the first global clinical trial results evaluating the investigational bispecific antibody pumitamig combined with chemotherapy as a first-line treatment for advanced non-small cell lung cancer.

This presentation presents the first global clinical trial results evaluating the investigational bispecific antibody pumitamig combined with chemotherapy as a first-line treatment for advanced non-small cell lung cancer. The therapy demonstrated strong antitumor activity and high rates of tumor shrinkage across both major disease histologies and all biomarker expression levels. Furthermore, the treatment regimen exhibited a manageable safety profile with minimal severe side effects, supporting its continued evaluation in an ongoing large-scale phase three clinical trial.

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