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News|Videos|December 23, 2025

Sonrotoclax (BGB-11417) Monotherapy in Patients With R/R MCL Previously Treated With a BTK Inhibitor: Results From a Phase 1/2 Study

Author(s)Michael Wang, MD

Michael Wang, M.D. discusses Sonrotoclax (BGB-11417) monotherapy in patients with R/R MCL previously treated with a BTK inhibitor: results from a phase 1/2 study

Michael Wang, M.D. discusses how, Sonrotoclax monotherapy showed strong and durable clinical activity in heavily pretreated patients with relapsed or refractory mantle cell lymphoma, with consistent benefit across high-risk subgroups. The treatment was generally well tolerated with manageable safety and a low rate of tumor lysis syndrome, supporting its potential as a promising new option in this setting.

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