Commentary|Articles|April 29, 2026

Staging Pitfalls, Biomarker-Guided Care, and Emerging Targets in Esophageal Cancer: Your Clinical Questions Answered

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Peter Enzinger, MD, discusses diagnostic pathways, the role of surgery, and ongoing trials of interest in esophageal cancer in this clinician-focused FAQ.

During Esophageal Cancer Awareness Month, OncLive® sat down with Peter Enzinger, MD, to break down and address key areas of uncertainty encountered in routine practice. The following FAQ, adapted from this conversation, provides insights into the clinical nuances shaping contemporary esophageal cancer diagnosis and management, including diagnostic and staging pitfalls, the role of curative-intent surgery and chemoradiation, and emerging biomarker-driven approaches of interest.

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