In a recent OncLive® Scientific Interchange, Roy S. Herbst, MD, PhD served as the moderator for a discussion on n using immunotherapy (IO) and targeted therapeutics in patients with NSCLC, to discuss factors impacting therapeutic selection and sequencing strategies in NSCLC, and to evaluate and obtain feedback on the evolving landscape of immunotherapy–based regimens in treating the disease.
The first MRD data from the phase 3 EXCALIBER-RRMM trial support iberdomide-based triplet therapy as early as first relapse, with PFS follow-up ongoing.
After nearly 7 years of follow-up, daratumumab added to VRd continued to improve PFS, PFS2, and sustained MRD negativity in transplant-eligible myeloma.
Daiichi Sankyo and Merck withdrew the I-DXd BLA in ES-SCLC after FDA discussions found phase 2 IDeate-Lung01 data insufficient for accelerated approval.
Monthly etentamig significantly improved response and PFS over standard available therapies in the phase 3 CERVINO trial, with low rates of high-grade CRS.