
GLP-1 receptor agonists are generating buzz for their metabolic benefits, as well as for their potential to directly combat breast cancer progression.
The emergence of ultrasensitive ctDNA and CSF testing may help alter monitoring strategies and adaptive clinical trial designs in metastatic breast cancer.
Ultrasensitive circulating tumor DNA (ctDNA) monitoring is increasingly reframing how metastatic breast cancer clinical trials are designed and how treatment decisions may be timed, shifting the focus from reacting to radiographic progression to intervening at the earliest molecular signs of resistance.1






