PRAME-directed therapies represent a novel approach in the treatment of advanced melanoma.
News|Videos|June 18, 2025
Updated Efficacy of Mutant-Selective PI3Kα Inhibitor RLY-2608 in Combination With Fulvestrant in Patients With PIK3CA-Mutant HR+/HER2– Advanced Breast Cancer: ReDiscover Trial
Author(s)Sarah Sammons, MD
Sarah Sammons, MD, presents updated results from the ReDiscover trial at the 2025 ASCO Annual Meeting in Chicago, demonstrating that the mutant-selective PI3Kα inhibitor RLY-2608 in combination with fulvestrant shows promising clinical activity and a manageable safety profile in patients with PIK3CA-mutant HR+/HER2– advanced breast cancer.
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