News|Videos|June 27, 2025

Updated Results From the Phase 1 Study of Sonrotoclax (BGB-11417), a Novel BCL2 Inhibitor, in Combination With Zanubrutinib for Relapsed/Refractory CLL/SLL, Demonstrate Deep and Durable Responses

Name: UPDATED RESULTS FROM THE PHASE 1 STUDY OF SONROTOCLAX (BGB-11417), A NOVEL BCL2 INHIBITOR, IN COMBINATION WITH ZANUBRUTINIB FOR RELAPSED/REFRACTORY CLL/SLL DEMONSTRATE DEEP AND DURABLE RESPONSES
Uploaded: 2025-06-27T12:00:00Z
Duration: OLRRO10m50s
Description: Chan Y. Cheah, MBBS, DMSc, shares insights on updated results from the phase 1 BGB-11417 trial that were presented at the 2025 EHA Congress in Milan, Italy. The longer follow-up data demonstrate the safety and efficacy of the sonrotoclax plus zanubrutinib combination in patients with relapsed or refractory chronic lympocytic leukemia and small lymphocytic lymphoma.

Author(s)Chan Cheah, MBBS

Chan Y. Cheah, MBBS, DMSc, shares insights on updated results from the phase 1 BGB-11417 trial that were presented at the 2025 EHA Congress in Milan, Italy. The longer follow-up data demonstrate the safety and efficacy of the sonrotoclax plus zanubrutinib combination in patients with relapsed or refractory chronic lympocytic leukemia and small lymphocytic lymphoma.

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Updated Results From the Phase 1 Study of Sonrotoclax (BGB-11417), a Novel BCL2 Inhibitor, in Combination With Zanubrutinib for Relapsed/Refractory CLL/SLL, Demonstrate Deep and Durable Responses

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