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Jacob Soumerai, MD

Articles by Jacob Soumerai, MD

BOVen

Multicenter Phase II Trial of Zanubrutinib, Obinutuzumab, and Venetoclax (BOVen) in Treatment-Naïve Chronic Lymphocytic Leukemia: 5-Year Follow Up, Retreatment Outcomes, and Impact of MRD Kinetics (ΔMRD400)

ByJacob Soumerai, MD

Dr. Jacob Soumerai provides a comprehensive 5-year follow-up on the multicenter Phase II trial of the BOVen regimen (zanubrutinib, obinutuzumab, and venetoclax) in treatment-naïve chronic lymphocytic leukemia, highlighting sustained undetectable minimal residual disease rates, retreatment outcomes, and the prognostic significance of MRD kinetics (ΔMRD400).

Data from an Ongoing Phase 1/1b Study BGB-11417-101

Sonrotoclax and Zanubrutinib as Frontline Treatment for CLL Demonstrates High MRD Clearance Rates with Good Tolerability: Data from an Ongoing Phase 1/1b Study BGB-11417-101

ByJacob Soumerai, MD

Dr. Jacob D. Soumerai presents updated data from the BGB-11417-101 study, highlighting the high efficacy, tolerability, and sustained minimal residual disease clearance achieved with the novel combination of sonrotoclax and zanubrutinib in patients with treatment-naïve chronic lymphocytic leukemia.

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