
John Mascarenhas, MD, discusses key data from the SENTRY trial of selinexor plus ruxolitinib in JAK inhibitor–naïve myelofibrosis.

John O. Mascarenhas, MD, is a professor of medicine at the Icahn School of Medicine at Mount Sinai; as well as director of the Center of Excellence for Blood Cancers and Myeloid Disorders, director of the Adult Leukemia Program, and a member of The Tisch Cancer Institute

John Mascarenhas, MD, discusses key data from the SENTRY trial of selinexor plus ruxolitinib in JAK inhibitor–naïve myelofibrosis.

John O. Mascarenhas, MD, discusses the ongoing investigation of various targeted therapies in myeloproliferative neoplasms.

John O. Mascarenhas, MD, details the investigation of novel targeted therapies in patients with myeloproliferative neoplasms.

John O. Mascarenhas, MD, discusses the potential role of imetelstat in the treatment of patients with myelofibrosis.

John Mascarenhas, MD, outlines the ongoing phase 3 IMpact-MF trial, evaluating imetelstat in relapsed/refractory myelofibrosis.

John O. Mascarenhas, MD, discussed findings from the IMproveMF trial investigating imetelstat plus ruxolitinib in patients with higher-risk myelofibrosis.

John Mascarenhas, MD, discusses first-line treatment decisions for patients with myelofibrosis.

John O. Mascarenhas, MD, discusses evolution of JAK inhibitors in the treatment landscape of myelofibrosis.

John O. Mascarenhas, MD, discusses updates from the phase 2 MANIFEST trial in patients with myelofibrosis.

John O. Mascarenhas, MD, discusses the role of genetic testing in myeloproliferative neoplasms.

John O. Mascarenhas, MD, discusses the potential significance of pacritinib in patients with myelofibrosis.

John O. Mascarenhas, MD, discusses emerging agents in myelofibrosis.

John O. Mascarenhas, MD, discusses the need to develop curative therapies in myelofibrosis.

John O. Mascarenhas, MD, discusses the potential role of pacritinib in myeloproliferative neoplasms.

John O. Mascarenhas, MD, discusses the impact of ruxolitinib in the myelofibrosis treatment paradigm.

September 26th 2025

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