
Katherine L. Nathanson, MD, discusses the impact of reversion mutations on resistance to PARP inhibitors across various DNA damage repair genes.

Your AI-Trained Oncology Knowledge Connection!


Katherine L. Nathanson, MD, serves as director of the Penn Medicine Center for Genomic Medicine and deputy director of Abramson Cancer Center. She is also principal investigator and Pearl Basser Professor of BRCA-related Research at Perelman School of Medicine, of the University of Pennsylvania.

Katherine L. Nathanson, MD, discusses the impact of reversion mutations on resistance to PARP inhibitors across various DNA damage repair genes.

Katherine L. Nathanson, MD, discusses the next steps for identifying novel mechanisms of resistance beyond reversion mutations in breast cancer.

Katherine L. Nathanson, MD, discusses the identification of reversion mutations in BRCA1/2 in response to therapy among patients with breast cancer.