Sophia R. O'Brien, MD

Sophia R. O'Brien, MD, is an assistant professor of clinical radiology in the Divisions of Nuclear Medicine and Breast Imaging, as well as the associate program director of the Diagnostic Radiology Residency, at Penn Medicine

Articles by Sophia R. O'Brien, MD

Megan Kruse, MD, breast medical oncologist, Cleveland Clinic; Sophia O’Brien, MD, assistant professor, clinical radiology, Divisions of Nuclear Medicine and Breast Imaging, associate program director, Diagnostic Radiology Residency, Penn Medicine

Breast Imaging Advances Emphasize the Importance of Patient-Focused Nuclear Medicine Collaboration: With Megan Kruse, MD; and Sophia O’Brien, MD

ByMegan Kruse, MD,Sophia R. O'Brien, MD

February 27th 2026

Drs Kruse and O’Brien highlight the various roles of imaging modalities in breast cancer diagnosis and treatment decision-making.

Dr O’Brien on Advances in Molecular Imaging in ER+ Breast Cancer

BySophia R. O'Brien, MD

July 26th 2023

Sophia R. O'Brien, MD, discusses recent advances in the diagnosis and staging of estrogen receptor–positive metastatic breast cancer.

Sophia R. O'Brien, MD

Articles by Sophia R. O'Brien, MD

Breast Imaging Advances Emphasize the Importance of Patient-Focused Nuclear Medicine Collaboration: With Megan Kruse, MD; and Sophia O’Brien, MD

Dr O’Brien on Advances in Molecular Imaging in ER+ Breast Cancer

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