
TOP study prospectively shows TP53-mutant EGFR lung cancer gains from first-line combination therapy, reshaping choices amid FLAURA2 and MARIPOSA.

TOP study prospectively shows TP53-mutant EGFR lung cancer gains from first-line combination therapy, reshaping choices amid FLAURA2 and MARIPOSA.

Experts unpack TOP trial data on TP53 co-mutations, guiding first-line EGFR lung cancer choices between osimertinib alone or with chemo.