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Real-world data showed that atezolizumab provided a benefit and was safe in patients with platinum-ineligible mUC and high comorbidities/functional status.

First-Line Atezolizumab Is Suitable in Platinum-Based Chemotherapy Ineligible mUC 

Tanya Gupta, MD, highlights the utility of adjuvant CDK4/6 and PARP inhibitors in patients with HR-positive, HER2-negative breast cancer.

Adjuvant CDK4/6 Inhibitors Lay a Solid Treatment Foundation in HR+, HER2– Breast Cancer

Ocular adverse effects stemming from mirvetuximab soravtansine did not significantly affect HRQOL in FRα-positive platinum-resistant ovarian cancer.

Ocular AEs From Mirvetuximab Soravtansine Do Not Impact HRQOL in FRα+ Platinum-Resistant Ovarian Cancer

Treatment with abemaciclib plus hormonal therapy showed promise in LGSOC/EEC but not in HGSOC, and larger studies are needed to validate these findings.

Abemaciclib/Hormonal Therapy Combo Yields Clinical Activity in LGSOC/EEC

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The California Institute for Regenerative Medicine has awarded a $6 million grant to USC investigators pioneering a new genetic therapy to treat glioblastoma.

New Grant Funds First-of-Its-Kind Gene Therapy to Treat Aggressive Brain Cancer

Ashling Wahner joined MJH Life Sciences in 2022. She produces 

, and helps ensure timely publication of news content and announcements from the FDA approval pipeline. She also attends conferences live and virtually to conduct video interviews and produce written coverage. Email: awahner@mjhlifesciences.com

 team as an assistant editor in 2025 after previously working on the 

R. Lor Randall, MD, FACS, discusses the development of a bone marrow matrix to study osteosarcoma and the model’s mechanisms of metastasis control.

Bioengineered Bone Marrow Model Reveals Potential New Strategies for Osteosarcoma Metastasis Control

Kyle Doherty joined MJH Life Sciences in 2021 and is the lead editor for 

as well as news and conference updates for OncLive.com. Email: kdoherty@mjhlifesciences.com

China’s NMPA has granted conditional approval to the EZH2 inhibitor tazemetostat for patients with relapsed/refractory EZH2-mutated follicular lymphoma.

NMPA Grants Conditional Approval to Tazemetostat for EZH2-Mutant R/R Follicular Lymphoma 

PLN-101095 plus pembrolizumab was safe and active in immune checkpoint inhibitor–refractory advanced solid tumors.

PLN-101095/Pembrolizumab Has Early Activity in ICI-Refractory Advanced Solid Tumors

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Evolving Approaches in the Management of Neuroendocrine Tumor-Associated Carcinoid Syndrome

Videos

Satya (Nanu) Das, MD, MSCI, Rodney Pommier, MD, and Jerome Zacks, MD, discuss how patients with neuroendocrine tumors progress to carcinoid syndrome and carcinoid heart disease, and how strategies for management have changed after key clinical trial data.

Funding provided by TerSera Therapeutics LLC. Content independently developed by OncLive.

Satya (Nanu) Das, MD, MSCI, provides an overview of the incidence rate and common symptoms of neuroendocrine tumors (NETs).

Overview of Neuroendocrine Tumors (NETs)

Rodney Pommier, MD, defines carcinoid syndrome and describes the process of diagnosis and clinical risk factors in patients.

Overview of Carcinoid Syndrome (CS)

Jerome Zacks, MD, explains carcinoid heart disease and its symptoms, and why it develops in some patients with NET-associated carcinoid syndrome.

Overview of Carcinoid Heart Disease (CHD)

Dr Satya (Nanu) Das discusses the typical management strategies for carcinoid syndrome-related symptoms, highlighting the use of somatostatin analogs.

Management of Carcinoid Syndrome-Related Symptoms

Dr Rodney Pommier gives an overview of somatostatin analog-refractory carcinoid syndrome and the recommended approaches for management in patients.

Diagnosis and Management of Somatostatin Analog-Refractory Carcinoid Syndrome

A medical oncologist reviews the currently available, NCCN-approved treatments for somatostatin analog-refractory carcinoid syndrome.

Available Treatment Options for Somatostatin Analog-Refractory Carcinoid Syndrome

Dr Pommier discusses key safety, efficacy, and quality of life data from the TELEPATH trial investigating the tryptophan hydroxylase inhibitor telotristat ethyl, while Dr Das comments on real-world data complements to the trial.

Data from the TELEPATH Trial and Real-World Analyses

Dr Jerome Zacks explains strategies to prevent, treat, and manage carcinoid heart disease, and emphasizes the need for multidisciplinary approaches.

Prevention, Treatment, and Management of Carcinoid Heart Disease

Experts comment on the current unmet needs for patients with neuroendocrine tumor-associated carcinoid syndrome.

Unmet Needs for Patients with Neuroendocrine Tumor-Associated Carcinoid Syndrome

Drs Das, Pommier, and Zacks share their advice for community physicians treating patients who have neuroendocrine tumors with carcinoid syndrome and carcinoid heart disease.

Advice for Community Physicians Treating Patients with Neuroendocrine Tumor-Associated Carcinoid Syndrome

EP: 1.Overview of Neuroendocrine Tumors (NETs)

EP: 2.Overview of Carcinoid Syndrome (CS)

EP: 3.Overview of Carcinoid Heart Disease (CHD)

EP: 4.Management of Carcinoid Syndrome-Related Symptoms

EP: 5.Diagnosis and Management of Somatostatin Analog-Refractory Carcinoid Syndrome

EP: 6.Available Treatment Options for Somatostatin Analog-Refractory Carcinoid Syndrome

EP: 7.Data from the TELEPATH Trial and Real-World Analyses

EP: 8.Prevention, Treatment, and Management of Carcinoid Heart Disease

EP: 9.Unmet Needs for Patients with Neuroendocrine Tumor-Associated Carcinoid Syndrome

EP: 10.Advice for Community Physicians Treating Patients with Neuroendocrine Tumor-Associated Carcinoid Syndrome

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