Can CAR T-Cell Therapy Be a Definitive Treatment for Adult R/R B-ALL Without Transplant? Long-Term Findings and Predictors of Sustained Remission for Obecabtagene Autoleucel
Jae Park, MD, presents long-term follow-up data from the FELIX study showing sustained remission in a subset of adult patients with relapsed/refractory B-cell acute lymphoblastic leukemia (B-ALL) treated with obecabtagene autoleucel (obe-cel), with predictors of long-term benefit and no new safety concerns identified.
The oral OMNI-EGFR inhibitor earned fast track status for advanced EGFR C797S–positive non–small cell lung cancer that progressed on a third-generation EGFR TKI.
Sapanisertib and serabelisib plus paclitaxel received FDA fast track designation for pretreated advanced PI3K/AKT/mTOR pathway–altered endometrial cancer.