Commentary|Videos|May 31, 2026

Dr Barlin on the Efficacy of Gotistobart Plus Pembrolizumab in Platinum-Resistant Ovarian Cancer

Joyce Nuqui Barlin, MD, shares the rationale for studying gotistobart plus pembrolizumab in patients with pretreated platinum-resistant ovarian cancer.

“We have not yet harnessed the immune system in ovarian cancer, so this was an attempt at using a combined-modality immunotherapy to see if we could have more success.”

Joyce Nuqui Barlin, MD, a gynecologic oncologist at Women’s Cancer Care Associates, part of St Peter’s Health Partners, discussed findings from a phase 2 trial (NCT05446298) investigating gotistobart (BNT316/ONC-392) plus pembrolizumab (Keytruda) in patients with pretreated platinum-resistant ovarian cancer.


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