Dr. Bendell on the Treatment of Microsatellite Stable Patients With CRC

Video

In Partnership With:

Johanna C. Bendell, MD, medical oncologist, Sarah Cannon Research Institute, discusses the treatment of patients with colorectal cancer (CRC) that are microsatellite stable.

Johanna C. Bendell, MD, medical oncologist, Sarah Cannon Research Institute, discusses the treatment of patients with colorectal cancer (CRC) that are microsatellite stable (MSS).

Bendell says that 95% of patients with metastatic CRC are not microsatellite high, and treatments for them must be developed. Preliminary results of combinations with immunotherapy have shown promising response rates.

The combination of the PD-1 inhibitor atezolizumab (Tecentriq) with the MEK inhibitor cobimetinib (Cotellic) showed impressive preliminary results, and the combination has now moved into a randomized phase III global study.

Related Videos
Shivaani Kummar, MBBS, FACP, Margaret and Lester DeArmond Endowed Chair of Cancer Research, Professor and Division Head, Division of Hematology/Medical Oncology, Oregon Health & Science University School of Medicine; co-director, Center for Experimental Therapeutics, co-deputy director, Knight Cancer Institute
Andre Goy, MD
Wenxin (Vincent) Xu, MD,
Guenther Koehne, MD, PhD
Alessandro Villa, DDS, PhD, MPH
Joseph Mikhael, MD
Michael Richardson, MD
Minesh Mehta, MD
Ruben Olivares, MD
Phillip J. Koo, MD