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Abhinav Deol, MD, discusses the role of CAR T-cell therapy in pediatric patients with acute lymphoblastic leukemia.
Abhinav Deol, MD, associate clinical professor, Barbara Ann Karmanos Cancer Institute, discusses the role of CAR T-cell therapy in pediatric patients with acute lymphoblastic leukemia (ALL).
Data have shown encouraging rates of complete remission (CR) among pediatric patients with ALL who are treated with CAR T-cell therapy, Deol says.
As such, CAR T-cell therapy may offer a potentially curative treatment option in this setting.
However, older patients with ALL who achieve a CR with CAR T-cell therapy require subsequent allogenic stem cell transplants to prevent relapse, Deol concludes.