Dr. Ellis Discusses the Cell-Proliferation Marker Ki67

Matthew J. Ellis, MD, PhD, director, Section of Breast Oncology, Division of Oncology, Department of Medicine, Washington University, St Louis, MO, discusses the cell-proliferation marker Ki67.

Ellis explains that the marker has been examined for many years because of its ability to show how many tumor cells are actively committed to cell division. An overexpression of Ki67 generally translates into a more aggressive clinical course. Despite this evidence there currently are not any guidelines or evidence to support testing for the marker in every tumor.