Dr. Epperla on CAR T-Cell Therapy in MCL

Narendranath Epperla, MBBS, MS, hematologist, The Ohio State University (OSU) Comprehensive Cancer Center, assistant professor in internal medicine, OSU, discusses chimeric antigen receptor (CAR) T-cell therapy for patients with mantle cell lymphoma (MCL).

There is not currently enough data for CAR T-cell therapy in MCL, explains Epperla. Based on the impressive data in the diffuse large B-cell lymphoma setting, it would not be surprising if CAR T-cell therapy showed impressive results in MCL. Using CAR T-cell therapy pre- or post-allogeneic stem cell transplant still needs to be determined.