
The selective ROCK2 inhibitor TDI01 generated organ-wide responses in previously treated moderate-to-severe chronic graft-versus-host disease, with the 400-mg dose performing best.
Hannah Goulart, MD, discusses the use of first-line blinatumomab plus ponatinib in Philadelphia chromosome–positive B-cell acute lymphoblastic leukemia.
“With 3 years of follow-up now, the majority of patients achieved a response [with blinatumomab plus ponatinib].”
Hannah Goulart, MD, a hematology oncology fellow at The University of Texas MD Anderson Cancer Center, discussed long-term follow-up findings from a phase 2 trial (NCT03263572) investigating first-line blinatumomab (Blincyto) plus ponatinib (Iclusig) in patients with Philadelphia chromosome–positive B-cell acute lymphoblastic leukemia.






