Dr. Grothey on Trastuzumab for Gastroesophageal Cancer


Dr. Axel Grothey from the Mayo Clinic on Trastuzumab for Gastroesophageal Cancer

Axel Grothey, MD, Professor of Oncology, Consultant, Medical Oncology, Mayo Clinic, discusses the first-line use of the targeted agent trastuzumab (Herceptin) to treat HER2-positive gastroesophageal cancer.

Trastuzumab is the first targeted agent to be used as a first-line therapy in gastroesophageal cancer. All patients with the disease should now be test for an overexpression of HER2. If patients are HER2-positive trastuzumab should be added to the standard chemotherapy, which is usually 5-fluorouracil and platinum agents such as cisplatin.

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