
The phase 3 OptiTROP-Lung06 trial showed a PFS improvement with sac-TMT plus pembrolizumab in PD-L1–negative NSCLC.
John V. Heymach, MD, PhD, chairman, Department of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, discusses the CheckMate-026 trial in lung cancer.
John V. Heymach, MD, PhD, chairman, Department of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, discusses the CheckMate-026 trial in lung cancer.
This randomized study compared frontline nivolumab (Opdivo) with chemotherapy in patients with lung cancer that had PD-L1 positivity.
Although the trial was negative, tumor mutation burden was found to be a good predictor of who was likely to derive benefit from immunotherapy as opposed to chemotherapy, says Heymach.




