
The FDA approved gedatolisib in PIK3CA wild-type breast cancer, granted full approval to selpercatinib in RET fusion+ tumors, and more.
Virginia Kaklamani, MD, DSc, discusses an analysis of ESR1 allelic frequencies in elacestrant-exposed ER+/HER2– metastatic ESR1-mutated breast cancer.
Virginia Kaklamani, MD, DSc, professor, medicine, Division of Hematology-Medical Oncology, The University of Texas (UT) Health Science Center San Antonio; leader, breast cancer program, Mays Cancer Center, UT Health San Antonio MD Anderson Cancer Center, discusses findings from an analysis of ESR1 variant allele frequencies (VAFs) in patients with estrogen receptor (ER)–positive, HER2-negative, advanced or metastatic ESR1-mutated breast cancer who received elacestrant (Orserdu) or standard of care (SOC) in the phase 3 EMERALD trial (NCT03778931).




