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|Videos|September 9, 2020

Supplements and Featured Publications

  • BTK Inhibitors in B-Cell Lymphomas
  • Volume 1
  • Issue 1

Dr. Leslie on the Utility of BTK Inhibitors in B-Cell Malignancies

Lori A. Leslie, MD, discusses the utility of BTK inhibitors in B-cell malignancies.

Lori A. Leslie, MD, lymphoma attending, John Theurer Cancer Center, discusses the utility of BTK inhibitors in B-cell malignancies.

BTK inhibitors target an enzyme that is necessary for B​-cell growth, says Leslie. ​Moreover, there are several approved indications ​for BTK inhibitors in chronic lymphocytic leukemia, small lymphocytic lymphoma, marginal zone lymphoma, mantle cell lymphoma ​(MCL), and ​Waldenström macroglobulinemia.

Notably, ibrutinib (Imbruvica) ​and acalabrutinib (Calquence) ​are 2 BTK inhibitors that are approved for patients with B-cell malignancies. Moreover, zanubrutinib (Brukinsa) is currently approved in relapsed/refractory MCL and is the subject of ongoing investigation in other B-cell malignancies, Leslie concludes. 

Articles in this issue

over 5 years ago

Bruton Tyrosine Kinase Inhibitors in B-Cell Lymphomas

over 5 years ago

Bruton Tyrosine Kinase Inhibitors in B-Cell Lymphomas

over 5 years ago

Dr. Ghosh on Approved BTK Inhibitors in B-Cell Malignancies

over 5 years ago

BTK Inhibitors Revolutionize Treatment in B-Cell Malignancies, But Require AE Awareness

over 5 years ago

Leslie Breaks Down the Growing Importance of BTK Inhibitors in B-Cell Malignancies

over 5 years ago

BTK Inhibitors Boost Outcomes in B-Cell Malignancies, But Challenges Remain

over 5 years ago

Dr. Ma on First- and Second-Generation BTK Inhibitors in B-Cell Malignancies

over 5 years ago

Building on Current Understandings of BTK Inhibition in CLL, MCL

over 5 years ago

Dr. Burke on Current FDA Indications for BTK Inhibitors in B-Cell Malignancies

over 5 years ago

Dr. Treon on the Evolution of BTK Inhibitors in Waldenström Macroglobulinemia

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