Dr. Manji on Treatment for BRAF-Mutant CRC

Video

In Partnership With:

Gulam A. Manji, MD, PhD, discusses clinical trials for patients with colorectal cancer harboring BRAF or other molecular abnormalities.

Gulam A. Manji, MD, PhD, director, Medical Oncology and Translational Research for The Pancreas Center, Herbert Irving Comprehensive Cancer Center, Columbia University Irving Medical Center, discusses clinical trials for patients with colorectal cancer (CRC) harboring BRAF or other molecular abnormalities.

Although prognosis is poor for patients with BRAF-mutant CRC, recent combination trials that target EGFR, MAK, and BRAF mutations are showing intriguing clinical activity, according to Manji.

Manji recommends that all patients with CRC who have BRAF mutations and other abnormalities should enroll onto biomarker-driven clinical trials to help researchers get solid data that show proven benefit.

Related Videos
A panel of 6 experts on colorectal cancer
A panel of 6 experts on colorectal cancer
Shivaani Kummar, MBBS, FACP, Margaret and Lester DeArmond Endowed Chair of Cancer Research, Professor and Division Head, Division of Hematology/Medical Oncology, Oregon Health & Science University School of Medicine; co-director, Center for Experimental Therapeutics, co-deputy director, Knight Cancer Institute
Andre Goy, MD
Wenxin (Vincent) Xu, MD,
Guenther Koehne, MD, PhD
Alessandro Villa, DDS, PhD, MPH
Joseph Mikhael, MD
Michael Richardson, MD
Minesh Mehta, MD