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Commentary|Videos|December 8, 2025

Dr Patel on the Efficacy of Anitocabtagene Autoleucel in R/R Multiple Myeloma

Fact checked by: Ashling Wahner , Chris Ryan

Krina K. Patel, MD, MSc, discusses the efficacy of anitocabtagene autoleucel in relapsed/refractory multiple myeloma from the iMMagine-1 trial.
“The biggest update is that the overall response rate is still 96%, and then [regarding] depth of response, the complete response [CR]/stringent CR rate is 74%. [We have] big minimal residual disease [MRD] data on the majority of our patients now. [In total], 95% of patients were MRD undetectable at [a sensitivity of] 10–5.”

Krina K. Patel, MD, MSc, an associate professor in the Department of Lymphoma/Myeloma in the Division of Cancer Medicine at The University of Texas MD Anderson Cancer Center, discussed findings from the phase 2 iMMagine-1 trial (NCT05396885) investigating anitocabtagene autoleucel in patients with relapsed/refractory multiple myeloma.

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