
The FDA has approved zidesamtinib in patients with locally advanced/metastatic ROS1+ NSCLC who received a prior ROS1 kinase inhibitor.
Dr. Pecora on the Pathway Inhibitor Cabozantinib (XL184)
Andrew L. Pecora, MD, FACP, CPE the Chief Innovations Officer, Professor and Vice President of Cancer Services at John Theurer Cancer Center on the pathway inhibitor cabozantinib.
Dr. Pecora says cabozantinib is an agent that is capable of blocking multiple pathways at the same time. In phase I trials, it has been shown to have activity in a broad array of solid tumors. It will demonstrate that by targeting specific pathways within a cancer cell, you can actually block the growth and, in some cases, kill the cancer cell in diseases that had not been sensitive to other therapies.


