Integrating Precision Pathways in HER2+ Gastroesophageal Adenocarcinoma—Testing, Treatment, and Supportive Care

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Episode Description

In this podcast, experts Geoffrey Y. Ku, MD, and Sunnie Kim, MD, discuss essential biomarker testing for advanced gastroesophageal adenocarcinoma, first-line treatment selection for HER2-positive metastatic disease in light of data from HERIZON-GEA-01 (NCT05152147), management of treatment-related diarrhea and other adverse events, and HER2 retesting at disease progression.

Acknowledgment of Educational Grant Support

This activity is supported by an educational grant from Jazz Pharmaceuticals, Inc.

Faculty:

Geoffrey Y. Ku, MD

Associate Attending Physician
Gastrointestinal Oncology and Cellular Therapy Services, Department of Medicine
Memorial Sloan Kettering Cancer Center
New York, NY

Sunnie Kim, MD

Associate Professor
Medical Oncologist
University of Colorado Anschutz Cancer Center
Aurora, CO

This podcast, including the narration, was produced by the PER^® editorial staff based on an online activity conducted with these faculty members. The narration was voiced by a PER staff member or by an AI tool.

To learn more about this topic, including information on including information on HER2 testing heterogeneity and pathologist interpretation, integration of PD-L1 status into first-line regimen selection, patient selection and monitoring for trastuzumab deruxtecan, and emerging HER2-targeted strategies in the perioperative setting, go to https://www.gotoper.com/courses/simulated-integrating-precision-pathways-in-her2-gastroesophageal-adenocarcinoma-testing-treatment-and-supportive-care.

Release Date

September 22, 2026

Expiration Date

September 22, 2027

Off-Label Disclosure and Disclaimer

This activity may or may not discuss investigational, unapproved, or off-label use of drugs. Learners are advised to consult prescribing information for any products discussed. The information provided in this activity is for education purposes only and is not meant to substitute for the independent clinical judgment of a healthcare professional relative to diagnostic, treatment, or management options for a specific patient’s medical condition. The opinions expressed in the content are solely those of the individual faculty members and do not reflect those of PER^® or any company that provided commercial support for this activity.