FDA has granted fast track designation to LYT-200 plus a hypomethylating agent in relapsed/refractory high-risk myelodysplastic syndromes.
Opinion|Videos|November 8, 2024
Intracranial Efficacy of Next-Generation ALK-Targeted Therapies
Panelists discuss the efficacy of ALK inhibitors in treating brain metastases, referencing data from the REMARK study, the CROWN trial, ALTA-3, and ALTA-1L/brigatinib, among others.
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- All: Please discuss the efficacy of ALK inhibitors in brain metastases.
- REMARK study (Xiong A, et al. 2024. WCLC. OA09.03)
- CROWN trial (Solomon BJ, et al. Lancet Respir Med. 2023)
- ALTA-3 (Yang JC, et al. J Thorac Oncol. 2023)
- ALTA-1L/brigatinib (Camidge DR, et al. J Clin Oncol. 2021)
- Others
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