Feature|Articles|November 6, 2026

LITESPARK-012, XmAb819, and PE-PE Data Headline Key Kidney Cancer Findings From ESMO 2026

Author(s)Ryan Kret
Fact checked by: Chris Ryan

The addition of belzutifan (Welireg) or quavonlimab to pembrolizumab plus lenvatinib (Lenvima) in the phase 3 LITESPARK-012 trial (NCT04736706), the ENPP3 x CD3 bispecific antibody XmAb819 in the phase 1 XmAb819-01 trial (NCT05433142), and perioperative pembrolizumab plus metastasis-directed therapy in the phase 2 PE-PE trial (NCT05578664) were among the most closely watched kidney cancer data and themes presented at the 2026 ESMO Congress.

Related to this article