Leal Sheds Light on Symptoms and Treatment of Lambert-Eaton Myasthenic Syndrome

Dr Leal discusses the symptoms commonly associated with Lambert-Eaton Myasthenic Syndrome, the prevalence of this disorder in concurrence with underlying cancers, and how amifampridine can help manage this disease by improving motor and autonomic symptoms.

Welcome to OncLive On Air®! I’m your host today, Ashling Wahner.

OncLive On Air® is a podcast from OncLive®, which provides oncology professionals with the resources and information they need to provide the best patient care. In both digital and print formats, OncLive® covers every angle of oncology practice, from new technology to treatment advances to important regulatory decisions.

In today’s episode, we had the pleasure of speaking with Ticiana Leal, MD, an associate professor in the Department of Hematology and Medical Oncology and the director of the Thoracic Medical Oncology Program in the Department of Hematology and Medical Oncology at Emory University School of Medicine. Dr Leal joined us to talk about Lambert-Eaton myasthenic syndrome (LEMS).

In our exclusive interview, Dr Leal discussed the symptoms commonly associated with this rare condition, including proximal muscle weakness that often contributes to difficulties walking and managing stairs. She also talked about the prevalence of LEMS in concurrence with underlying cancers such as small cell lung cancer, and emphasized how the use of amifampridine (Firdapse), the first FDA-approved treatment for LEMS, is tolerable and can help manage this disease by improving motor and autonomic symptoms.


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