Feature|Articles|June 26, 2025

Ongoing Trials Aim to Remove Carboplatin from TCHP and Reduce Treatment Cycles in HER2+ Breast Cancer

Author(s)Ashley Chan
Fact checked by: Kyle Doherty

As the HER2-positive breast cancer landscape continues to evolve, the omission of carboplatin in TCHP could drive significant change.

Within the past decade, the HER2-positive breast cancer landscape has demonstrated significant improvements. However, coming off the heels of the 2025 ASCO Annual Meeting, data from the phase 2 CompassHER2 pCR trial (NCT04266249) and the phase 3 neoCARHP study (NCT04858529) have potentially helped move the HER2-positive breast cancer treatment paradigm towards a less intensive chemotherapy regimen.

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