Santos Summarizes Key Updates From EMPOWER-Lung 1 and EMPOWER-Lung 3 With Cemiplimab in NSCLC

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Dr Santos discusses findings from the EMPOWER-Lung 3 trial of cemiplimab plus chemotherapy in patients with advanced non–small cell lung cancer, as well as data from subgroup analyses of the EMPOWER-Lung 1 trial of cemiplimab monotherapy in patients with NSCLC and a PD-L1 score over 50%.

Welcome to OncLive On Air®! I’m your host today, Ashling Wahner.

OncLive On Air is a podcast from OncLive®, which provides oncology professionals with the resources and information they need to provide the best patient care. In both digital and print formats, OncLive covers every angle of oncology practice, from new technology to treatment advances to important regulatory decisions.

In today’s episode, sponsored by Regeneron Pharmaceuticals, we had the pleasure of speaking with Edgardo S. Santos, MD, FACP, about 2023 updates from the phase 3 EMPOWER-Lung 1 (NCT03088540) and EMPOWER-Lung 3 (NCT03409614) clinical trials. Dr Santos is an associate professor of clinical biomedical sciences at Florida Atlantic University in Boca Raton, as well as vice chairman of the Florida Society of Clinical Oncology Membership Committee.

In our exclusive interview, Dr Santos discussed key long-term findings from the EMPOWER-Lung 3 trial of cemiplimab-rwlc (Libtayo) plus chemotherapy in patients with advanced non–small cell lung cancer (NSCLC), considerations that arise when evaluating data from subgroup analyses of the EMPOWER-Lung 1 trial of cemiplimab monotherapy in patients with NSCLC and a PD-L1 score over 50%, and how these data emphasize the importance of conducting long-term follow-up analyses in clinical trials.

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Edgardo Santos, MD, FACP, FCCP
Edgardo Santos, MD, FACP, FCCP