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News|Videos|February 16, 2024

The TROPION-Breast01 Trial: Datopotamab Deruxtecan in HR+, HER2- Breast Cancer

Author(s)Laura Huppert, MD, Yara Abdou, MD

The TROPION-Breast01 trial studied the antibody-drug conjugate datopotamab deruxtecan (Dato-DXd) in previously treated HR+, HER2- breast cancer patients and showed improved progression-free survival to 7 months compared to 4.5 months with standard chemotherapy, with less high grade toxicity observed with Dato-DXd.

Episodes in this series

EP. 1 An Overview of HR+, HER2- Metastatic Breast Cancer

EP. 1 An Overview of HR+, HER2- Metastatic Breast Cancer

EP. 2 Overview of the Treatment Landscape for HR+, HER2- Advanced or Metastatic Breast Cancer

EP. 2 Overview of the Treatment Landscape for HR+, HER2- Advanced or Metastatic Breast Cancer

EP. 3 The MAINTAIN Trial: Ribociclib in Combination With Endocrine Therapy in Patients With Metastatic Breast Cancer

EP. 3 The MAINTAIN Trial: Ribociclib in Combination With Endocrine Therapy in Patients With Metastatic Breast Cancer

EP. 4 Approaches to Repeat Hormone Receptor and HER2 Status Testing Before Initiating Later Lines of Therapy

EP. 4 Approaches to Repeat Hormone Receptor and HER2 Status Testing Before Initiating Later Lines of Therapy

EP. 5 CAPItello-291 Trial: Evaluating Capivasertib Plus Fulvestrant in Patients With HR+, HER2- Advanced Breast Cancer

EP. 5 CAPItello-291 Trial: Evaluating Capivasertib Plus Fulvestrant in Patients With HR+, HER2- Advanced Breast Cancer

EP. 6 The EMERALD Trial: Elacestrant in Patients with HR+, HER2- Advanced Breast Cancer

EP. 6 The EMERALD Trial: Elacestrant in Patients with HR+, HER2- Advanced Breast Cancer

EP. 7 The TROPION-Breast01 Trial: Datopotamab Deruxtecan in HR+, HER2- Breast Cancer

EP. 7 The TROPION-Breast01 Trial: Datopotamab Deruxtecan in HR+, HER2- Breast Cancer

EP. 8 Approaches to Treatment Decision-Making and Sequencing for HR+, HER2- Metastatic Breast Cancer

EP. 8 Approaches to Treatment Decision-Making and Sequencing for HR+, HER2- Metastatic Breast Cancer

EP. 9 Exciting Ongoing Studies in the Treatment of HR+, HER2- Metastatic Breast Cancer

EP. 9 Exciting Ongoing Studies in the Treatment of HR+, HER2- Metastatic Breast Cancer

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