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Opinion|Videos|November 19, 2024

Treatment Sequencing in Relapsed/Refractory CLL: Key Factors Influencing Decision-Making

Author(s)Nitin Jain, MD, Joanna M. Rhodes, MD, MSCE

Panelists discuss how they approach treatment sequencing in relapsed/refractory chronic lymphocytic leukemia (CLL), considering primary factors such as prior therapies, mechanisms of resistance, patient characteristics, and treatment goals to optimize the order and selection of subsequent therapies for improved long-term outcomes.

Episodes in this series

EP. 1 The Current Treatment Landscape for R/R CLL

EP. 1 The Current Treatment Landscape for R/R CLL

EP. 2 Impact of Prior BTKi vs BCL2i Therapy on Treatment Decision-Making in CLL

EP. 2 Impact of Prior BTKi vs BCL2i Therapy on Treatment Decision-Making in CLL

EP. 3 Key Patient-Specific Factors Guiding Treatment Selection in CLL

EP. 3 Key Patient-Specific Factors Guiding Treatment Selection in CLL

EP. 4 Tailoring Treatment Approaches for Rapid vs. Slow Disease Progression in CLL

EP. 4 Tailoring Treatment Approaches for Rapid vs. Slow Disease Progression in CLL

EP. 5 Assessing Resistance to First-Line BTK Inhibitor Therapy: The Emergine Role of Testing in CLL

EP. 5 Assessing Resistance to First-Line BTK Inhibitor Therapy: The Emergine Role of Testing in CLL

EP. 6 Pirtobrutinib in the Management of R/R CLL: Updates from the BRUIN Trial

EP. 6 Pirtobrutinib in the Management of R/R CLL: Updates from the BRUIN Trial

EP. 7 Application of Pirtobrutinib in R/R CLL: Expert Perspectives

EP. 7 Application of Pirtobrutinib in R/R CLL: Expert Perspectives

$EP. 8 Influence of TLS Risk and Patient Preferences on Treatment Selection in Relapsed/Refractory CLL$

EP. 8 Influence of TLS Risk and Patient Preferences on Treatment Selection in Relapsed/Refractory CLL

$EP. 9 Navigating treatment strategies for patients with multi-refractory CLL: CAR-T, ASCT, and PI3K Inhibitors$

EP. 9 Navigating treatment strategies for patients with multi-refractory CLL: CAR-T, ASCT, and PI3K Inhibitors

EP. 10 Sequencing and Combination Strategies with Pirtobrutinib and CAR-T Therapy in R/R CLL

EP. 10 Sequencing and Combination Strategies with Pirtobrutinib and CAR-T Therapy in R/R CLL

$EP. 11 Treatment Sequencing in Relapsed/Refractory CLL: Key Factors Influencing Decision-Making$

EP. 11 Treatment Sequencing in Relapsed/Refractory CLL: Key Factors Influencing Decision-Making

EP. 12 Emerging role of doublet triplet therapies in R/R CLL: Expert Perspectives

EP. 12 Emerging role of doublet triplet therapies in R/R CLL: Expert Perspectives

EP. 13 The Impact of Emerging Resistance Patterns on Treatment Sequencing in R/R CLL

EP. 13 The Impact of Emerging Resistance Patterns on Treatment Sequencing in R/R CLL

$EP. 14 Multidisciplinary Approach to Managing Treatment for Relapsed/Refractory CLL$

EP. 14 Multidisciplinary Approach to Managing Treatment for Relapsed/Refractory CLL

Video content above is prompted by the following:

How do you approach treatment sequencing for relapsed/refractory CLL, and what are the primary factors that influence your sequencing decisions?

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