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Commentary|Videos|May 22, 2025

When to Test for KMT2A Rearrangements and Other Alterations in Pediatric Acute Leukemia

Author(s)Lia Gore, MD, Sarah K. Tasian, MD

Fact checked by: Chris Ryan

Lia Gore, MD, and Sarah K. Tasian, MD, discuss the optimal timing of testing for KMT2A rearrangements in pediatric acute leukemia.

Episodes in this series

$Lia Gore, MD, and Sarah K. Tasian, MD, discuss current treatment trends in pediatric relapsed/refractory acute leukemia.$

EP. 1 Current Treatment Strategies in Pediatric R/R AML and ALL

$Lia Gore, MD, and Sarah K. Tasian, MD, on the significance of the FDA approval of revumenib in KMT2A-rearranged relapsed/refractory acute leukemia.$

EP. 2 Implications of the FDA Approval of Revumenib in KMT2A+ R/R Acute Leukemia

Lia Gore, MD, and Sarah K. Tasian, MD, discuss the optimal timing of testing for KMT2A rearrangements in pediatric acute leukemia.

EP. 3 When to Test for KMT2A Rearrangements and Other Alterations in Pediatric Acute Leukemia

$Lia Gore, MD, and Sarah K. Tasian, MD, discuss the use of 25-mg tablets of revumenib in pediatric KMT2A-translocated relapsed/refractory acute leukemia.$

EP. 4 Integrating 25-mg Tablets of Revumenib Into Pediatric R/R Acute Leukemia Management

$Lia Gore, MD, and Sarah K. Tasian, MD, discuss treatment expectations with revumenib in pediatric relapsed/refractory acute leukemia.$

EP. 5 Breaking Down Treatment Expectations With Revumenib in Pediatric KMT2A+ R/R Acute Leukemia

Lia Gore, MD, and Sarah K. Tasian, MD, discuss key factors for the management of pediatric acute leukemia.

EP. 6 Factors to Consider in Pediatric Acute Leukemia Management

Lia Gore, MD, and Sarah K. Tasian, MD, discuss ongoing research in pediatric acute leukemia.

EP. 7 Treatment Trends and Ongoing Research in Pediatric Acute Leukemia

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