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Oncology Conference Articles
Everolimus Shows Robust Activity in Lung/GI NETs
Everolimus improved progression-free survival by 7.1 months compared with placebo in patients with lung/gastrointestinal (GI) neuroendocrine tumors, representing a 52% reduction in the risk of progression or death.
Lu-Dotatate Shows Unprecedented PFS in Midgut NETs
Lu-Dotatate demonstrated an unprecedented 79% reduction in the risk of progression or death compared with high-dose octreotide LAR in patients with progressive, metastatic midgut neuroendocrine tumors.
Novel Drug Relieves Carcinoid Syndrome Symptoms
Telotristat etiprate, a novel serotonin synthesis inhibitor, helped reduce daily bowel movements for patients with carcinoid syndrome no longer responding to standard-of-care therapies.
Combining Chemo With mTOR Inhibitors Shows Promise in pNETS
Combining the chemotherapy streptozotocin with drugs that target the mTOR pathway may be an effective way to treat pancreatic neuroendocrine tumors.
Biomarker Needed for CAPTEM Regimen in Metastatic Pancreatic NETs
The efficacy of several predictive markers previously thought to determine which patients might respond to temozolomide-based therapy could not be validated for patients with pancreatic neuroendocrine tumors.
Full Surgical Resection Should Be Performed Whenever Possible for Gastroenteropancreatic NETs
Full surgical resection of gastroenteropancreatic neuroendocrine tumors is associated with a greater than 90% survival rate at five years.
FDA Approval in HCC, Breakthrough Designation in MCL, and More
Dabrafenib/Trametinib Combo Induces High Responses in BRAF V600E-Mutant Biliary Tract Cancer
Treatment Goals in Refractory mCRC
FDA Approves Third Trastuzumab Biosimilar
Olaratumab Falls Short in Phase III Soft Tissue Sarcoma Trial
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