Dr. Garcia-Carbonero on Quality of Life Impact of FOLFIRI Plus Ramucirumab in mCRC

Rocio Garcia-Carbonero, MD, PhD
Published: Friday, Aug 07, 2015



Rocio Garcia-Carbonero, MD, PhD, Universidad de Sevilla, discusses the quality of life results from the RAISE study.

The RAISE study was a phase III randomized, double-blind study of FOLFIRI plus ramucirumab or placebo in patients with metastatic colorectal cancer (mCRC) after first-line therapy with bevacizumab, oxaliplatin, or fluoropyrimidine.

Quality of life scores were calculated based on physical functioning, role functioning, emotional functioning, fatigue, appetite loss, and constipation. Results found that there was a transient worsening in quality of life for the FOLFIRI plus ramucirumab arm compared to the placebo plus FOLFIRI arm. However, differences in most quality of life scores were not significantly significant between the two arms.


Rocio Garcia-Carbonero, MD, PhD, Universidad de Sevilla, discusses the quality of life results from the RAISE study.

The RAISE study was a phase III randomized, double-blind study of FOLFIRI plus ramucirumab or placebo in patients with metastatic colorectal cancer (mCRC) after first-line therapy with bevacizumab, oxaliplatin, or fluoropyrimidine.

Quality of life scores were calculated based on physical functioning, role functioning, emotional functioning, fatigue, appetite loss, and constipation. Results found that there was a transient worsening in quality of life for the FOLFIRI plus ramucirumab arm compared to the placebo plus FOLFIRI arm. However, differences in most quality of life scores were not significantly significant between the two arms.

View Conference Coverage
Online CME Activities
TitleExpiration DateCME Credits
Medical Crossfire®: Key Questions for the Use of Immunotherapy Throughout the Disease Continuum for NSCLC in an Era of Rapid DevelopmentSep 29, 20181.5
Provider and Caregiver Connection™: Addressing Patient Concerns While Managing GlioblastomaSep 29, 20182.0
Publication Bottom Border
Border Publication
x